Annual report [Section 13 and 15(d), not S-K Item 405]

Strategic Agreements - Additional Information (Details)

v3.25.1
Strategic Agreements - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
Nov. 30, 2023
Dec. 31, 2018
Dec. 31, 2024
Dec. 31, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Derivative liabilities - royalty agreement     $ 1,647,000 $ 1,014,000
Gain on extinguishment     0 23,098,000
Ligand Development Funding Agreement [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
One-time payment amount agreed to fund development   $ 10,000,000    
Maximum payments to receive upon achievement of milestones   $ 8,000,000    
Agreement royalty term period from first sale   15 years    
Agreement termination notice period   90 days    
Aggregate potential future milestone payments remaining under arrangement     5,000,000 5,000,000
Derivative liabilities - royalty agreement     $ 1,600,000 $ 1,000,000
Effective interest rate percentage of potential future royalty payments     39.90% 38.90%
Non-cash interest expense (income)     $ 3,900,000 $ (6,300,000)
Ligand Development Funding Agreement [Member] | Maximum [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty percentage   9.80%    
Reduction of royalty tier percentage on annual worldwide net sales   2.00%    
Ligand Development Funding Agreement [Member] | Minimum [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty percentage   5.00%    
Reduction of royalty tier percentage on annual worldwide net sales   1.00%    
Amended Ligand Agreement [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Additional amount received in return for increase in future tiered royalties $ 5,000,000      
Gain on extinguishment $ 23,100,000      
Term period for option to purchase additional product revenue participation rights 10 years      
Amended Ligand Agreement [Member] | Maximum [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty percentage 9.80%      
Amended Ligand Agreement [Member] | Minimum [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty percentage 8.00%      
Palvella [Member] | Maximum [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty percentage 5.00%      
Upfront payment $ 7,500,000      
Palvella [Member] | Minimum [Member]        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Royalty percentage 1.00%      
Upfront payment $ 1,500,000