Annual report pursuant to Section 13 and 15(d)

Subsequent Events - License and Collaboration Agreement and Non-Exclusive Anticalin Platform Technology License Agreement with Seattle Genetics (Details)

v3.8.0.1
Subsequent Events - License and Collaboration Agreement and Non-Exclusive Anticalin Platform Technology License Agreement with Seattle Genetics (Details) - USD ($)
$ in Thousands
12 Months Ended
Feb. 08, 2018
Dec. 31, 2017
Dec. 31, 2016
Subsequent Event [Line Items]      
Milestone payments   $ 12,573 $ 1,655
Seattle Genetics | Subsequent Event      
Subsequent Event [Line Items]      
Contract termination due to material breach, additional notice period 90 days    
Seattle Genetics | License and Collaboration Agreement | Subsequent Event      
Subsequent Event [Line Items]      
Period after effective date agreements may be terminated 12 months    
Contract termination advance notice period 90 days    
Agreement termination advance notice period if pivotal study has been initiated 180 days    
Agreement termination notice period upon material breach by the Company 90 days    
Seattle Genetics | License and Collaboration Agreement | Maximum | Subsequent Event      
Subsequent Event [Line Items]      
Milestone payments $ 1,200,000    
Seattle Genetics | Upfront Payment | Subsequent Event      
Subsequent Event [Line Items]      
Allocable arrangement consideration $ 30,000