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Commitments and Contingencies - Additional Information (Detail)
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0 Months Ended | 3 Months Ended | 12 Months Ended | 12 Months Ended | 3 Months Ended | 12 Months Ended | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Dec. 23, 2014
USD ($)
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Dec. 23, 2014
EUR (€)
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Mar. 31, 2015
USD ($)
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Mar. 31, 2015
EUR (€)
|
Dec. 31, 2014
USD ($)
Sublease
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Dec. 31, 2013
USD ($)
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Dec. 31, 2014
License Agreement [Member]
IBA GmbH [Member]
USD ($)
|
Dec. 31, 2014
License Agreement [Member]
TUM [Member]
USD ($)
|
Mar. 31, 2015
Out License Fee [Member]
USD ($)
|
Dec. 31, 2014
Out License Fee [Member]
USD ($)
|
Dec. 31, 2014
Out License Fee [Member]
EUR (€)
|
Dec. 31, 2014
General and Administrative [Member]
USD ($)
|
Dec. 31, 2013
General and Administrative [Member]
USD ($)
|
Dec. 31, 2014
Research and Development [Member]
USD ($)
|
Dec. 31, 2013
Research and Development [Member]
USD ($)
|
Mar. 31, 2015
TUM [Member]
USD ($)
|
Mar. 31, 2014
TUM [Member]
USD ($)
|
Dec. 31, 2014
TUM [Member]
USD ($)
|
Dec. 31, 2013
TUM [Member]
USD ($)
|
Mar. 31, 2015
TUM [Member]
Out License Fee [Member]
USD ($)
|
Mar. 31, 2015
TUM [Member]
Out License Fee [Member]
EUR (€)
|
Dec. 31, 2014
TUM [Member]
Out License Fee [Member]
USD ($)
|
Dec. 31, 2014
TUM [Member]
Out License Fee [Member]
EUR (€)
|
Mar. 31, 2015
TUM [Member]
License Agreement [Member]
USD ($)
|
Dec. 31, 2014
TUM [Member]
License Agreement [Member]
USD ($)
|
Mar. 31, 2014
TUM [Member]
License Agreement [Member]
USD ($)
|
Dec. 31, 2013
TUM [Member]
License Agreement [Member]
USD ($)
|
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| Loss Contingencies [Line Items] | |||||||||||||||||||||||||||
| Annual license payment | $ 36,303 | $ 60,505 | $ 14,057 | $ 17,131 | $ 66,461 | $ 66,390 | |||||||||||||||||||||
| Agreement expiration date | 2024 | 2027 | |||||||||||||||||||||||||
| Notification period | 8 months | ||||||||||||||||||||||||||
| Rent expense | 268,621 | 289,991 | 72,600 | 72,498 | 217,799 | 217,493 | |||||||||||||||||||||
| Number of sub lease agreements | 6 | ||||||||||||||||||||||||||
| Out-License Fee amount | 400,000 | 300,000 | 300,000 | 3,400,000 | 3,000,000 | 2,500,000 | |||||||||||||||||||||
| Amount of loss contingency liability | 291,081 | 327,937 | 373,357 | 373,059 | |||||||||||||||||||||||
| Counterclaim amount filed | 3,060,827 | 2,529,400 | |||||||||||||||||||||||||
| Reserved liability | 327,937 | 271,000 | |||||||||||||||||||||||||
| Claims and counterclaims amount | $ 4,235,350 | € 3,500,000 | |||||||||||||||||||||||||