Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Operating activities:    
Net loss $ (15,072) $ (25,138)
Adjustments to reconcile net loss to net cash provided by operating activities:    
Depreciation 405 268
Stock-based compensation 3,665 1,962
Other (376) 87
Changes in operating assets and liabilities 19,370 77,269
Net cash provided by operating activities 7,992 54,448
Investing activities:    
Purchases of property and equipment (1,133) (1,131)
Proceeds from maturity of investments 64,490 0
Purchases of investments (67,015) 0
Net cash used in investing activities (3,658) (1,131)
Financing activities:    
Proceeds from exercise of stock options 983 366
Proceeds from exercise of warrants 314 3,127
Issuance of common stock, net of issuance costs 47,207 0
Net cash provided by financing activities 48,504 3,493
Effect of exchange rate change on cash and cash equivalents (1,234) 3,755
Net increase in cash and cash equivalents 51,604 60,565
Cash and cash equivalents at beginning of period 37,878 29,356
Cash and cash equivalents at end of period 89,482 89,921
Supplemental cash flow disclosures:    
Cash paid for income taxes 902 0
Net unrealized loss on investments 1,096 0
Property and equipment included in accounts payable $ 222 $ 121