Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Operating activities:    
Net loss $ (8,917) $ (18,079)
Adjustments to reconcile net loss to net cash provided by operating activities:    
Depreciation 275 213
Stock-based compensation 2,355 1,312
Other 54 23
Changes in operating assets and liabilities 28,584 35,780
Net cash provided by operating activities 22,351 19,249
Investing activities:    
Purchases of property and equipment (808) (842)
Proceeds from maturity of investments 10,974 0
Purchases of investments (67,222) 0
Net cash used in investing activities (57,056) (842)
Financing activities:    
Proceeds from exercise of stock options 839 178
Proceeds from exercise of warrants 182 1,287
Issuance of common stock, net of issuance costs 47,207 0
Net cash provided by financing activities 48,228 1,465
Effect of exchange rate change on cash and cash equivalents (825) 1,096
Net increase in cash and cash equivalents 12,698 20,968
Cash and cash equivalents at beginning of period 37,878 29,356
Cash and cash equivalents at end of period 50,576 50,324
Supplemental cash flow disclosures:    
Net unrealized loss on investments 1,667 0
Property and equipment included in accounts payable $ 202 $ 19