Annual report pursuant to Section 13 and 15(d)

Revenue - Revenue from Product Sales (Detail)

v2.4.1.9
Revenue - Revenue from Product Sales (Detail) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Income Statement [Abstract]    
License fees $ 473,039us-gaap_LicenseAndServicesRevenue $ 5,159,425us-gaap_LicenseAndServicesRevenue
Research and development services 876,619us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned 3,591,855us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCompensationEarned
Milestone payments 3,184,988us-gaap_RevenueRecognitionMilestoneMethodRevenueRecognized 1,128,630us-gaap_RevenueRecognitionMilestoneMethodRevenueRecognized
Government grants 830,408us-gaap_RevenueFromGrants 2,547,382us-gaap_RevenueFromGrants
Total Revenue $ 5,365,054us-gaap_Revenues $ 12,427,292us-gaap_Revenues